Isoprophyl myristate

Isoprophyl myristate
Compound Structure:
Synonyms: propan-2-yl tetradecanoate; Isopropyl tetradecanoate; Estergel; Isomyst; Bisomel; Promyr; Tetradecanoic acid, 1-methylethyl ester; Deltyl Extra; Kesscomir; Tegester; 1-Methylethyl tetradecanoate; Deltylextra; Myristic acid isopropyl ester; Kessco isopropy
Compound ID: NMPC-1164
PubChem ID:

8042

Molecular Formula: C17H34O2
Canonical SMILES: CCCCCCCCCCCCCC(=O)OC(C)C
InChIKey: AXISYYRBXTVTFY-UHFFFAOYSA-N
About the compound:

Isopropyl myristate is a moisturizer with polar characteristics used in cosmetics and topical medical preparations to ameliorate the skin absorption. Isopropyl myristate has been largely studied and impulsed as a skin penetration enhancer. At the moment the primary usage for which isopropyl myristate is formally indicated is as the active ingredient in a non-prescription pediculicide rinse.

GHS Hazard Statements

H315 (99.58%): Causes skin irritation [Warning Skin corrosion/irritation]

First Aid

For immediate first aid:

• Ensure adequate decontamination.

• Perform artificial respiration if not breathing, using appropriate equipment.

• Administer CPR if necessary.

• Immediately flush contaminated eyes with gently flowing water.

• Do not induce vomiting; if vomiting occurs, position patient to prevent aspiration.

• Keep patient calm and maintain normal body temperature, seek medical attention.

For basic treatment:

• Establish airway, suction if necessary.

• Assist ventilation if needed, administer oxygen.

• Monitor for pulmonary edema, shock, and seizures, treat as necessary.

• Flush eyes immediately with water, irrigate continuously with saline during transport.

• Rinse mouth, administer water for ingestion.

• Cover skin burns with sterile dressings after decontamination.

For advanced treatment:

• Consider intubation for airway control in severe cases.

• Use positive-pressure ventilation if beneficial.

• Consider drug therapy for pulmonary edema and severe bronchospasm.

• Monitor cardiac rhythm, treat arrhythmias.

• Start IV fluid administration, monitor for hypovolemia and fluid overload.

• Treat seizures with appropriate medication.

• Use proparacaine hydrochloride for eye irrigation.

Overall, ensure thorough decontamination, airway management, and seek medical attention promptly.

Currance, P.L. Clements, B., Bronstein, A.C. (Eds).; Emergency Care For Hazardous Materials Exposure. 3Rd edition, Elsevier Mosby, St. Louis, MO 2005,

Properties:

Chemical and Physical Properties

Property Name

Property Value

Molecular Weight

270.5 g/mol

XLogP3-AA

7.2

Hydrogen Bond Donor Count

0

Hydrogen Bond Acceptor Count

2

Rotatable Bond Count

14

Exact Mass

270.255880323 g/mol

Monoisotopic Mass

270.255880323 g/mol

Topological Polar Surface Area

26.3Ų

Heavy Atom Count

19

Formal Charge

0

Complexity

199

Isotope Atom Count

0

Defined Atom Stereocenter Count

0

Undefined Atom Stereocenter Count

0

Defined Bond Stereocenter Count

0

Undefined Bond Stereocenter Count

0

Covalently-Bonded Unit Count

1

Compound Is Canonicalized

Yes

Physical Description

Liquid

Boiling Point

588 K (315 °C) at 760 mm Hg

Melting Point

3 °C

Density

0.847 - 0.855

Solubility 

Soluble in castor oil, cottonseed oil, acetone, chloroform, ethyl acetate, ethanol, toluene, and mineral oil; practically insoluble in glycerol, propylene glycol

Vapor Pressure

0.0000935 [mmHg]

Source: PubChem        

Source Species: Bryophyllum pinnatum
Piliostigma thonningii.
Plumeria alba
Download SDF